Description

11Beta,13-Dihydrolactucin is a sesquiterpene lactone compound, a key intermediate and reference standard in phytochemical and pharmaceutical research. Its significance lies in its role as a precursor or active marker for the synthesis and analysis of bioactive lactucin derivatives. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries who require reliable, well-characterized chemical entities for method development, quality control, and biological activity studies.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of lactucin-related compounds in drug development and quality control laboratories.
• Bioactive Compound Research: Serves as a critical intermediate or standard in studies investigating the anti-inflammatory, analgesic, or other pharmacological properties of sesquiterpene lactones.
• Natural Product Synthesis: Acts as a key building block or precursor in the semi-synthesis of complex natural products and their analogs for structure-activity relationship (SAR) studies.
• Botanical Extract Standardization: Employed as a certified reference material to quantify lactucin and related sesquiterpenes in plant materials, such as chicory (Cichorium intybus) and lettuce (Lactuca species).
• Analytical Method Development: Utilized to develop and validate chromatographic methods (e.g., HPLC, LC-MS) for the separation and detection of sesquiterpene lactones in complex matrices.

Basic Information

Product Name	11Beta,13-Dihydrolactucin
CAS No.	83117-63-9
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	11β,13-Dihydrolactucin; 11β,13-Dihydro-lactucin; (3aR,4S,9aS,9bR)-4-Hydroxy-9-(hydroxymethyl)-3,6,9-trimethylidene-3a,4,5,8,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione; Dihydrolactucin; 11β,13-Dihydro lactucin
EINECS	Contact for details

Quality Control

Our 11Beta,13-Dihydrolactucin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.