Description

6-Amidino-2-Naphthyl-4-Aminomethylbenzoate Dimethanesulfonate is a high-purity organic salt compound with significant biological activity. This compound is valued for its role as a key intermediate and active pharmaceutical ingredient (API) in advanced research and therapeutic development. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of serine protease inhibitors and other targeted therapeutic molecules.
• Biochemical Research: Used as a reference standard and active compound in enzymatic studies and mechanism-of-action research.
• Protease Inhibitor Development: Serves as a core structural component for developing inhibitors targeting thrombin, trypsin, and related enzymes.
• Anticoagulant Research: Investigated for potential applications in the development of novel antithrombotic and anticoagulant drugs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing complex, high-value specialty chemicals.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic kits and assays for clinical laboratories.

Basic Information

Product Name	6-Amidino-2-Naphthyl-4-Aminomethylbenzoate Dimethanesulfonate
CAS No.	82956-02-3
Molecular Formula	C21H23N3O6S2
Molecular Weight	477.55 g/mol
Synonyms	6-Amidino-2-naphthyl 4-(aminomethyl)benzoate dimethanesulfonate; 4-Amidinonaphthalen-2-yl 4-(aminomethyl)benzoate methanesulfonate salt; 4-(Aminomethyl)benzoic Acid 6-Amidino-2-naphthyl Ester Dimethanesulfonate; FUT-187 (as mesylate salt); Nafamostat Impurity; Nafamostat Mesylate Related Compound; (6-Amidino-2-naphthyl) 4-(aminomethyl)benzoate bis(methanesulfonate); Guanidino naphthyl ester mesylate
EINECS	Contact for details

Quality Control

Our 6-Amidino-2-Naphthyl-4-Aminomethylbenzoate Dimethanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.