Description

Mabuprofen CAS NO 82821-47-4 is a high-purity pharmaceutical intermediate and active ingredient of significant commercial importance. It serves as a critical building block in the synthesis of advanced non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents. This compound is essential for manufacturers in the pharmaceutical, fine chemical, and research sectors seeking reliable, high-quality raw materials for API production and novel drug development.

Application

• Pharmaceutical API Synthesis: A key intermediate in the industrial-scale production of ibuprofen and related propionic acid derivative NSAIDs.
• Fine Chemical Manufacturing: Used in the synthesis of more complex, value-added chemical entities for medicinal chemistry.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D for developing new anti-inflammatory and analgesic compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of finished dosage forms.
• Reference Standard: Utilized as an analytical reference standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Mabuprofen
CAS No.	82821-47-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-(4-Isobutylphenyl)propionic acid precursor; α-Methyl-4-(2-methylpropyl)benzeneacetic acid intermediate; Mabuprofen; Ibuprofen intermediate; p-Isobutylhydratropic acid derivative; 4-Isobutyl-α-methylphenylacetic acid related compound; [1,1'-Biphenyl]-4-acetic acid, α-methyl-4-(2-methylpropyl)-; (RS)-2-(4-isobutylphenyl)propanoic acid synthesis intermediate
EINECS	Contact for details

Quality Control

Our Mabuprofen is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. The product undergoes rigorous analytical testing, including chromatographic purity assays and identification tests, to meet the stringent requirements of pharmaceutical ingredient supply. Certificates of Analysis (COA) documenting purity, related substances, and other critical parameters are available for every batch. We support compliance with cGMP, ICH guidelines, and relevant pharmacopeial standards (USP/EP) as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.