Description

2,4-Dibromobutyryl Chloride is a versatile and highly reactive brominated acid chloride intermediate. Its value lies in its ability to introduce both bromine atoms and a reactive acyl chloride moiety into target molecules, facilitating the synthesis of complex organic compounds. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a precise building block for active ingredient development and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring bromine substitution for bioactivity or as a synthetic handle.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the dibromo structure imparts specific biological activity.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce bromine and ester/amide functionalities into polymer chains, altering material properties like flame retardancy.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for nucleophilic acyl substitution reactions, enabling the preparation of amides, esters, and ketones.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of advanced electronic materials and dyes due to its ability to form rigid, conjugated structures.
• Peptide Chemistry: Can act as a coupling agent or protecting group reagent in the synthesis of modified peptides and peptidomimetics.

Basic Information

Product Name	2,4-Dibromobutyryl Chloride
CAS No.	82820-87-9
Molecular Formula	C4H5Br2ClO
Molecular Weight	264.34 g/mol
Synonyms	2,4-Dibromobutanoyl Chloride; Butanoyl Chloride, 2,4-dibromo-; 2,4-Dibromo-1-butanoyl Chloride; 2,4-Dibromobutyric Acid Chloride; α,γ-Dibromobutyryl Chloride; NSC 401122; 2,4-Dibromobutanoic Acid Chloride
EINECS	Contact for details

Quality Control

Our 2,4-Dibromobutyryl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by GC/HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.