Description

(2R,5S)-2,5-Dimethyl-1-Phenyl-Piperazine is a chiral piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a crucial pharmaceutical intermediate and a versatile chiral building block for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Chiral Ligand & Catalyst Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and enantioselective synthesis.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Academic & Industrial R&D: Utilized in research exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	(2R,5S)-2,5-Dimethyl-1-Phenyl-Piperazine
CAS No.	82776-49-6
Molecular Formula	C12H18N2
Molecular Weight	190.28 g/mol
Synonyms	(2R,5S)-1-Phenyl-2,5-dimethylpiperazine; (2R,5S)-1-Phenyl-2,5-dimethyl-piperazine; (R,S)-1-Phenyl-2,5-dimethylpiperazine; 1-Phenyl-2,5-dimethylpiperazine (2R,5S)-; 2,5-Dimethyl-1-phenylpiperazine (2R,5S)-; UNII-1C8Q7K5K8F; 1C8Q7K5K8F; (2R,5S)-2,5-Dimethyl-1-phenylpiperazine
EINECS	Contact for details

Quality Control

Our (2R,5S)-2,5-Dimethyl-1-Phenyl-Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.