Description

Boc-Freidinger'S Lactam CAS NO 82611-48-1 is a protected lactam derivative widely used as a key chiral building block in advanced organic synthesis. This compound is essential for the efficient construction of complex molecular architectures, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers developing peptide-based therapeutics and other bioactive molecules requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those with constrained peptide or peptidomimetic structures.
• Peptide Chemistry: Serves as a protected scaffold for introducing specific amino acid sequences or conformational constraints into peptides.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template to induce stereoselectivity in the formation of new carbon-carbon or carbon-heteroatom bonds.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities targeting various disease pathways.
• Process Chemistry Development: Used for scaling up synthetic routes in pilot plants and commercial manufacturing under GMP conditions.
• Academic Research: A valuable reagent for methodology development and the total synthesis of natural products in university and institutional labs.

Basic Information

Product Name	Boc-Freidinger'S Lactam
CAS No.	82611-48-1
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	(3S,6S)-3-[(tert-Butoxycarbonyl)amino]-1-azabicyclo[4.3.0]nonan-2-one; (3S,6S)-3-[(tert-Butoxycarbonyl)amino]octahydro-1H-isoindol-2-one; Boc-(S,S)-Freidinger Lactam; (S,S)-Boc-Freidinger Lactam; tert-Butyl (2-oxo-1,3,3a,4,5,6,7,7a-octahydroisoindol-3-yl)carbamate; Freidinger Lactam Boc Derivative; (3S,3aS,7aS)-3-[(tert-Butoxycarbonyl)amino]octahydro-1H-isoindol-2-one
EINECS	Contact for details

Quality Control

Our Boc-Freidinger'S Lactam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.