Description

Insulin, Disulfide-Des-Ala(B30)- CAS NO 82537-96-0 is a specifically modified insulin analog where the alanine residue at position B30 has been removed and the A and B chains are linked by disulfide bonds. This engineered structure is of significant value for advanced biochemical research and pharmaceutical development, particularly in the study of insulin's structure-activity relationships and receptor binding mechanisms. It is primarily required by research institutions, biotechnology companies, and pharmaceutical developers focused on metabolic disease research, novel therapeutic agent design, and high-purity reference standard production.

Application

• Biochemical Research: Serves as a critical reference standard and tool compound for investigating insulin signaling pathways, folding, and stability.
• Pharmaceutical Development: Used in the research and pre-clinical stages for developing novel insulin analogs and delivery systems.
• Metabolic Disease Studies: Applied in academic and industrial labs to model diabetes and understand hormone-receptor interactions.
• Analytical Standard: Employed as a high-purity calibrant in chromatographic (HPLC, UPLC) and mass spectrometric analyses for quality control.
• Peptide Chemistry Studies: Utilized as a model compound in studies focusing on disulfide bond formation, protein engineering, and synthetic methodology.

Basic Information

Product Name	Insulin, Disulfide-Des-Ala(B30)-
CAS No.	82537-96-0
Molecular Formula	C254H377N65O75S6
Molecular Weight	~5807.5 g/mol
Synonyms	Des-Ala(B30)-Insulin; B30-Des-Alanine Insulin; Insulin (Des-Ala-B30); Insulin analog (B30-Des-Ala); [Des-AlaB30]-Insulin; Human Insulin Des-B30-Ala; Insulin, Desalanine-B30-; Disulfide-linked Des-AlaB30 Insulin
EINECS	Contact for details

Quality Control

Our Insulin, Disulfide-Des-Ala(B30)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, peptide mapping, and mass spectrometry for identity confirmation to ensure it meets rigorous research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.