Description

Piperazino-Acetaldehyde-Diethylacetal is a versatile acetal-protected aldehyde derivative of piperazine, serving as a critical synthetic intermediate in advanced organic synthesis. This compound matters for its role in introducing the piperazine moiety, a privileged scaffold in medicinal chemistry, into target molecules under controlled conditions. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical development, and the synthesis of complex specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing piperazine rings, such as antipsychotics, antidepressants, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides where the piperazine structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers with tailored chemical properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research in exploring new heterocyclic compounds and reaction methodologies.
• Custom Synthesis: Provides a protected aldehyde functionality for multi-step synthetic routes requiring selective deprotection and further functionalization.

Basic Information

Product Name	Piperazino-Acetaldehyde-Diethylacetal
CAS No.	82516-06-1
Molecular Formula	C10H22N2O2
Molecular Weight	202.30 g/mol
Synonyms	1-(1,1-Diethoxyethyl)piperazine; 1-(Diethoxymethyl)piperazine; 1-Piperazineacetaldehyde Diethyl Acetal; N-(Diethoxymethyl)piperazine; 2,2-Diethoxy-1-(piperazin-1-yl)ethane; Piperazine-1-acetaldehyde Diethyl Acetal; Acetaldehyde, (1-piperazinyl)-, diethyl acetal
EINECS	Contact for details

Quality Control

Our Piperazino-Acetaldehyde-Diethylacetal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets high-grade specifications suitable for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.