Description

(4Ar)-4,4A,5,6,7,8,8Aβ,9-Octahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-7α,9α-Diol is a complex, high-purity furan-based diol compound with a unique octahydronaphtho-fused ring structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for synthesizing complex organic molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in steroid-like or complex polycyclic therapeutic agents.
• Asymmetric Synthesis: Valuable chiral building block in stereoselective organic synthesis, enabling the construction of molecules with specific three-dimensional configurations.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities for drug discovery programs.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, agrochemicals, and high-value performance materials requiring complex fused-ring architectures.
• Academic & Industrial R&D: Serves as a reference standard and starting material in chemical research focused on natural product synthesis and methodology development.

Basic Information

Product Name	(4Ar)-4,4A,5,6,7,8,8Aβ,9-Octahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-7α,9α-Diol
CAS No.	82462-28-0
Molecular Formula	C₁₉H₂₈O₃
Molecular Weight	304.43 g/mol
Synonyms	7α,9α-Dihydroxy-3,4aβ,5β-trimethyl-4,4a,5,6,7,8,8aβ,9-octahydronaphtho[2,3-b]furan; (4aR)-4,4a,5,6,7,8,8aβ,9-Octahydro-3,4aβ,5β-trimethylnaphtho[2,3-b]furan-7α,9α-diol; 7α,9α-Dihydroxy-3,4aβ,5β-trimethyl-4,4a,5,6,7,8,8aβ,9-octahydro-2H-naphtho[2,3-b]furan; Octahydronaphthofuran Diol Derivative; 82462-28-0; 7α,9α-Dihydroxy-3,4aβ,5β-trimethyl-4,4a,5,6,7,8,8aβ,9-octahydronaphtho[2,3-b]furan-4a-carbaldehyde (related); Trimethyloctahydronaphthofurandiol
EINECS	Contact for details

Quality Control

Our (4Ar)-4,4A,5,6,7,8,8Aβ,9-Octahydro-3,4Aβ,5β-Trimethylnaphtho[2,3-B]Furan-7α,9α-Diol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.