Description

Arteannuin A CAS NO 82442-48-6 is a high-purity sesquiterpene lactone, a key bioactive constituent isolated from the plant *Artemisia annua* L. This compound is of significant interest for its role as a direct precursor in the biosynthesis of the potent antimalarial agent, artemisinin. It serves as a critical reference standard and starting material for pharmaceutical research, development, and quality control processes targeting antimalarial therapies and other bioactive investigations.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of artemisinin and related derivatives in pharmacopeial testing (e.g., USP, EP).
• Biosynthesis Research: Acts as a crucial intermediate in studies elucidating and optimizing the biosynthetic pathway of artemisinin within *Artemisia annua*.
• Medicinal Chemistry & Drug Development: Serves as a high-purity building block or precursor for the semi-synthesis of novel artemisinin analogs and derivatives with potential therapeutic applications.
• Analytical Method Development: Essential for developing and validating precise analytical methods, such as HPLC, LC-MS, and GC-MS, for the quantification of sesquiterpene lactones in plant extracts and finished products.
• Biological Activity Screening: Utilized in in vitro and in vivo studies to investigate its own pharmacological properties beyond its role as a biosynthetic intermediate.
• Quality Control in Herbal Extracts: Employed to standardize and authenticate the quality of *Artemisia annua* extracts intended for research or commercial use.

Basic Information

Item	Detail
Product Name	Arteannuin A
CAS No.	82442-48-6
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	Arteannuic Acid A; Arteannuine A; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; Artemisinin Precursor; Qinghaosu Intermediate
EINECS	Contact for details

Quality Control

Every batch of Arteannuin A is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure it meets the exacting standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA), including results for identity, purity (HPLC), and related substances, is supplied with each shipment. Our quality protocols are designed to support compliance with ICH guidelines and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.