Description

2-(Chloromethyl)-6-Methylpyrazine is a versatile pyrazine derivative, a key heterocyclic building block prized for its reactive chloromethyl group. This compound matters for its role as a crucial intermediate in the synthesis of complex molecules, enabling the introduction of functionalized pyrazine moieties. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrazine core contributes to biological activity.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing alkylpyrazines, which are important aroma compounds for food and fragrance applications.
• Material Science Research: Employed as a monomer or functionalization agent in the development of specialty polymers and organic electronic materials.
• Chemical Research & Development: A valuable building block for constructing diverse heterocyclic libraries in drug discovery and combinatorial chemistry.

Basic Information

Product Name	2-(Chloromethyl)-6-Methylpyrazine
CAS No.	81831-69-8
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	6-Methyl-2-(chloromethyl)pyrazine; 2-Chloromethyl-6-methylpyrazine; (6-Methylpyrazin-2-yl)methyl chloride; 2-(Chloromethyl)-6-methyl-1,4-diazine; 6-Methyl-2-pyrazinylmethyl chloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-Methylpyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.