Description

2-(Chloromethyl)-5-Methylpyrazine is a versatile pyrazine derivative that serves as a critical building block in advanced organic synthesis. Its reactive chloromethyl group makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active ingredients, flavor and fragrance compounds, and functional materials who require a reliable, high-purity synthetic precursor.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents and other heterocyclic drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyrazine core contributes to biological activity.
• Flavor & Fragrance Industry: Serves as a precursor for alkylpyrazines, which are important aroma compounds contributing nutty, roasted, and earthy notes in food flavors and perfumery.
• Material Science Research: Employed in the synthesis of ligands for catalysis, organic semiconductors, and other functional organic materials.
• Chemical Research & Development: A versatile reagent for nucleophilic substitution reactions, enabling the introduction of the 5-methylpyrazinyl moiety into more complex molecular architectures.

Basic Information

Product Name	2-(Chloromethyl)-5-Methylpyrazine
CAS No.	81831-68-7
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	5-Methyl-2-(chloromethyl)pyrazine; 2-Chloromethyl-5-methylpyrazine; (5-Methylpyrazin-2-yl)methyl chloride; 5-Methyl-2-pyrazinemethyl chloride; 2-Chloromethyl-5-methyl-1,4-diazine
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-5-Methylpyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We are committed to meeting the stringent requirements of our global customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.