Description

1,4:3,6-Dianhydro-2-Deoxy-2-((3-Phenylpropyl)Amino)-L-Iditol 5-Nitrate Monohydrochloride is a high-purity, specialized organic compound with a complex molecular structure. This compound is significant for its role as a key intermediate or active pharmaceutical ingredient (API) in advanced medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology firms, and academic institutions engaged in the synthesis of novel therapeutic agents, particularly those targeting cardiovascular or metabolic pathways.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of complex drug candidates, especially those with nitrate ester functionalities.
• Cardiovascular Research: Used in the development and study of new vasodilatory or anti-anginal compounds due to the presence of the nitrate ester group.
• Metabolic Pathway Studies: Serves as a tool compound in biochemical research to investigate enzyme interactions and metabolic processes involving sugar-derived molecules.
• Preclinical Development: Employed in the formulation and efficacy testing of new chemical entities (NCEs) during early-stage drug discovery.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis (HPLC, LC-MS).
• Academic Synthesis: A valuable substrate for advanced organic chemistry research and methodology development in universities and institutes.

Basic Information

Product Name	1,4:3,6-Dianhydro-2-Deoxy-2-((3-Phenylpropyl)Amino)-L-Iditol 5-Nitrate Monohydrochloride
CAS No.	81786-46-1
Molecular Formula	C15H21N3O6 • HCl
Molecular Weight	375.81 g/mol (Free base: 339.35 g/mol)
Synonyms	2-Deoxy-2-[(3-phenylpropyl)amino]-1,4:3,6-dianhydro-L-iditol 5-nitrate hydrochloride; L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-((3-phenylpropyl)amino)-, 5-nitrate, monohydrochloride; ISDN Derivative; Isosorbide Dinitrate Analog; 2-Amino-2-deoxyisosorbide 5-nitrate derivative HCl
EINECS	Contact for details

Quality Control

Our 1,4:3,6-Dianhydro-2-Deoxy-2-((3-Phenylpropyl)Amino)-L-Iditol 5-Nitrate Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing purity (typically by HPLC), related substances, residual solvents, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.