Description

L-Iditol, 1,4:3,6-Dianhydro-2-Deoxy-2-(Dimethylamino)-, 5-Nitrate, Mon Ohydrochloride is a specialized, high-purity organic salt derivative of isosorbide, a sugar alcohol. This compound is valued for its role as a key chiral intermediate and building block in advanced pharmaceutical synthesis and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex, functionalized molecules in custom synthesis and process chemistry.
• Academic & Industrial R&D: A valuable reagent for methodological studies in asymmetric synthesis, catalysis, and medicinal chemistry.
• Bioconjugate Chemistry: Potential use in the design of drug-linker systems for antibody-drug conjugates (ADCs) and other targeted therapies.

Basic Information

Product Name	L-Iditol, 1,4:3,6-Dianhydro-2-Deoxy-2-(Dimethylamino)-, 5-Nitrate, Mon Ohydrochloride
CAS No.	81786-30-3
Molecular Formula	C8H15N3O6 • HCl
Molecular Weight	285.68 g/mol (Free base: 249.22 g/mol)
Synonyms	1,4:3,6-Dianhydro-2-deoxy-2-(dimethylamino)-L-iditol 5-nitrate hydrochloride; 2,5-Dideoxy-2-(dimethylamino)-1,4:3,6-dianhydro-L-iditol 5-nitrate hydrochloride; Isosorbide-2-nitrate-2-dimethylamino hydrochloride; L-Isosorbide-2-dimethylamino-5-nitrate hydrochloride; 2-Dimethylamino-1,4:3,6-dianhydro-2,5-dideoxy-L-iditol 5-nitrate hydrochloride; (3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(methylcarbamate) nitrate derivative (hydrochloride salt).
EINECS	Contact for details

Quality Control

Our L-Iditol, 1,4:3,6-Dianhydro-2-Deoxy-2-(Dimethylamino)-, 5-Nitrate, Mon Ohydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.