Description

Phosphazene Base P1-T-Bu is a powerful, non-ionic, sterically hindered organic superbase. This compound is valued for its exceptional basicity, low nucleophilicity, and high thermal stability, making it a superior catalyst and reagent in demanding synthetic transformations. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for deprotonation reactions and as an initiator in polymerization processes.

Application

• Polymerization Catalyst: As an efficient initiator for the ring-opening polymerization of cyclic esters (e.g., lactides, lactones) to produce biodegradable polymers and polycarbonates.
• Pharmaceutical Synthesis: Facilitating challenging deprotonation steps in the synthesis of active pharmaceutical ingredients (APIs), especially where strong, non-nucleophilic bases are required.
• Agrochemical Intermediate Production: Used in the synthesis of complex molecules for crop protection agents, leveraging its ability to promote reactions under mild conditions.
• Organic Synthesis Reagent: For regioselective and stereoselective reactions, including isomerizations, eliminations, and the generation of reactive carbanions.
• Materials Science Research: In the development of novel polymeric materials, dendrimers, and other advanced functional materials requiring precise molecular control.
• Lithium-Ion Battery Electrolyte Additive: Investigated for use as a stabilizer or performance enhancer in electrolyte formulations due to its chemical stability.

Basic Information

Product Name	Phosphazene Base P1-T-Bu
CAS No.	81675-81-2
Molecular Formula	C18H40N3P
Molecular Weight	329.50 g/mol
Synonyms	tert-Butylimino-tris(dimethylamino)phosphorane; P1-t-Bu Phosphazene Base; t-Bu-P1; BTPP (tert-Butylimino-tris(pyrrolidino)phosphorane is a related compound, often confused); Verkade's Superbase (P1-t-Bu); 2-tert-Butylimino-2-diethylamino-1,3-dimethylperhydro-1,3,2-diazaphosphorine; Schwesinger Base (P1-t-Bu variant); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Phosphazene Base P1-T-Bu is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing specifications such as assay (by NMR or titration), residual solvent content, and moisture levels (Karl Fischer) are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.