Description

cis-2,3-Diphenylpiperazine is a versatile chiral piperazine derivative and a key synthetic intermediate in organic chemistry. Its rigid, substituted piperazine core makes it a valuable building block for constructing complex molecular architectures with specific stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a crucial precursor in the synthesis of biologically active molecules, including potential drug candidates and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) active compounds, receptor ligands, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its structural motif can contribute to specific biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis to produce enantiomerically pure compounds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex heterocyclic compounds.
• Material Science: Potential monomer or building block for the synthesis of specialized polymers and advanced organic materials.

Basic Information

Product Name	cis-2,3-Diphenylpiperazine
CAS No.	81601-99-2
Molecular Formula	C16H18N2
Molecular Weight	238.33 g/mol
Synonyms	(2R,3S)-2,3-Diphenylpiperazine; (2S,3R)-2,3-Diphenylpiperazine; cis-2,3-Diphenylpiperazine; rel-(2R,3S)-2,3-Diphenylpiperazine; 2,3-Diphenylpiperazine (cis-); Piperazine, 2,3-diphenyl-, cis-; (±)-cis-2,3-Diphenylpiperazine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of cis-2,3-Diphenylpiperazine is monitored through in-process controls and final release testing, which typically includes identity confirmation, purity assay, and chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.