Description

3-[2-[4-[3-(Trifluoromethyl)Phenyl]Piperazin-1-Yl]Ethyl]Benzooxazol-2- One is a high-purity, advanced pharmaceutical intermediate featuring a benzoxazolone core linked to a trifluoromethylphenyl-piperazine moiety. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is essential for research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential antipsychotic, antidepressant, and anxiolytic drug candidates targeting serotonin and dopamine receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel CNS-active compounds.
• Biochemical Tool Compound: Serves as a reference standard or ligand in receptor binding assays and pharmacological studies.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage drug development.
• Academic Research: Utilized in universities and research institutes for neuropharmacology and organic synthesis projects.

Basic Information

Product Name	3-[2-[4-[3-(Trifluoromethyl)Phenyl]Piperazin-1-Yl]Ethyl]Benzooxazol-2- One
CAS No.	81513-96-4
Molecular Formula	C20H20F3N3O2
Molecular Weight	391.39 g/mol
Synonyms	3-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2(3H)-benzoxazolone; 2(3H)-Benzoxazolone, 3-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-; 3-(2-(4-(3-(Trifluoromethyl)phenyl)piperazin-1-yl)ethyl)benzo[d]oxazol-2(3H)-one; CAS 81513-96-4; TFMPP-Benzooxazolone Derivative; Trifluoromethylphenylpiperazinyl Ethyl Benzoxazolone
EINECS	Contact for details

Quality Control

Our 3-[2-[4-[3-(Trifluoromethyl)Phenyl]Piperazin-1-Yl]Ethyl]Benzooxazol-2- One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.