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1-Hexadecanoyl-2-[cis-9-Octadecanoyl]-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Ammonium Salt CAS NO 81490-05-3
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CAS No.:81490-05-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Hexadecanoyl-2-[cis-9-Octadecanoyl]-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Ammonium Salt is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylglycerol ammonium salt. This compound is a critical building block for advanced lipid-based formulations, offering superior control over membrane properties and stability. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors who require precise, well-defined lipid components for their applications.
Application
- Liposome & Nanoparticle Formulation: A key structural component for creating stable, uniform liposomes and lipid nanoparticles (LNPs) used in drug delivery systems, including mRNA vaccines and cancer therapeutics.
- Biomimetic Membrane Research: Used to construct model cell membranes for studying membrane-protein interactions, permeability, and biophysical processes.
- Diagnostic Reagents: Incorporated into diagnostic kits and assays as a membrane stabilizer or signal enhancer.
- Cosmetic & Dermal Delivery: Employed in high-end cosmetic formulations as an emulsifier and penetration enhancer for active ingredients.
- Cell Culture & Cryopreservation: Acts as a protective agent in cell culture media and cryoprotectant solutions to maintain cell viability.
- Material Science: Serves as a precursor or additive for creating functionalized surfaces, coatings, and smart materials.
Basic Information
| Product Name | 1-Hexadecanoyl-2-[cis-9-Octadecanoyl]-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Ammonium Salt |
| CAS No. | 81490-05-3 |
| Molecular Formula | C40H80NO10P |
| Molecular Weight | 766.04 g/mol |
| Synonyms | Ammonium 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol); POPG-NH4; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ammonium salt; POPG ammonium salt; PG(16:0/18:1(9Z)) ammonium salt; Phosphatidylglycerol (16:0/18:1) ammonium salt; (2R)-2,3-Dihydroxypropyl (2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl hydrogen phosphate, ammonium salt |
| EINECS | Contact for details |
Quality Control
Our 1-Hexadecanoyl-2-[cis-9-Octadecanoyl]-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Ammonium Salt is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Solubility | Soluble in chloroform, methanol; forms dispersions in water |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 10 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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