Description

Etofenamate Stearate is a high-purity, non-steroidal anti-inflammatory drug (NSAID) ester prodrug, synthesized from etofenamate and stearic acid. This compound is valued for its enhanced lipophilicity and stability, which can improve dermal penetration and bioavailability in topical formulations. It is primarily sought by pharmaceutical manufacturers and R&D laboratories for the development of advanced analgesic and anti-inflammatory creams, gels, and transdermal patches.

Application

• Topical Analgesic Formulations: A key active pharmaceutical ingredient (API) in creams, ointments, and gels for the relief of muscle pain, arthritis, and localized inflammation.
• Transdermal Drug Delivery Systems: Used in the development of patches and other sustained-release delivery systems due to its prodrug characteristics.
• Veterinary Pharmaceuticals: Incorporated into topical preparations for managing pain and inflammation in animals.
• Pharmaceutical Intermediates: Serves as a critical synthetic intermediate for further chemical modification and the creation of novel NSAID derivatives.
• Cosmeceutical R&D: Investigated for potential use in cosmetic products targeting skin redness and irritation.
• Reference Standard: Supplied as a certified reference material for quality control and analytical method development in pharmaceutical testing laboratories.

Basic Information

Product Name	Etofenamate Stearate
CAS No.	81427-97-6
Molecular Formula	C31H52N2O5
Molecular Weight	532.76 g/mol
Synonyms	2-(2-Hydroxyethoxy)ethyl 2-[(3-Trifluoromethyl)phenyl]amino]benzoate, Octadecanoate; Etofenamate Octadecanoate; Flogovital; Rheumon; Etofenamate Stearic Acid Ester; 2-(2-Hydroxyethoxy)ethyl N-(α,α,α-Trifluoro-m-tolyl)anthranilate Stearate
EINECS	Contact for details

Quality Control

Our Etofenamate Stearate is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identification by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are supplied with each shipment, ensuring compliance with cGMP and ICH Q7 guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.