Description

3-Bromo-1H-Pyrazolo[3,4-B]Pyrazine is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used to create novel heterocyclic compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological systems.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	3-Bromo-1H-Pyrazolo[3,4-B]Pyrazine
CAS No.	81411-68-9
Molecular Formula	C5H3BrN4
Molecular Weight	198.01 g/mol
Synonyms	3-Bromo-1H-pyrazolo[3,4-b]pyrazine; 3-Bromopyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine, 3-bromo-; 3-Bromo-1H-pyrazolo[3,4-b]pyrazine; 3-Bromo-1H-pyrazolo[3,4-b]pyrazine; 81411-68-9; 3-Bromo-1H-pyrazolo[3,4-b]pyrazine; Pyrazolo[3,4-b]pyrazine, 3-bromo-1H-
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Pyrazolo[3,4-B]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.