Description

Imidazo(2,1-B)(1,3,5)Benzothiadiazepine, 5-(4-Methyl-1-Piperazinyl)-, (Z)-2-Butenedioate(1:1) is a high-purity, specialized heterocyclic compound with a complex fused-ring structure. This material is a critical intermediate in advanced pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery of new drugs targeting central nervous system disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those with benzothiadiazepine or imidazole pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Biochemical Research: Serves as a tool compound for investigating biological pathways and receptor interactions in vitro.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Preclinical Development: Utilized in the early-stage development of potential new chemical entities (NCEs) for various disease models.

Basic Information

Product Name	Imidazo(2,1-B)(1,3,5)Benzothiadiazepine, 5-(4-Methyl-1-Piperazinyl)-, (Z)-2-Butenedioate(1:1)
CAS No.	81382-52-7
Molecular Formula	C18H19N5O4S
Molecular Weight	401.44 g/mol
Synonyms	5-(4-Methylpiperazin-1-yl)imidazo[2,1-b][1,3,5]benzothiadiazepine fumarate; (Z)-But-2-enedioic acid;5-(4-methylpiperazin-1-yl)imidazo[2,1-b][1,3,5]benzothiadiazepine; Imidazo[2,1-b][1,3,5]benzothiadiazepine, 5-(4-methyl-1-piperazinyl)-, (2Z)-2-butenedioate (1:1); Fumaric acid salt of 5-(4-Methylpiperazinyl)imidazobenzothiadiazepine; 81382-52-7; 5-(4-Methyl-1-piperazinyl)imidazo[2,1-b][1,3,5]benzothiadiazepine fumarate
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Quality Control

Our Imidazo(2,1-B)(1,3,5)Benzothiadiazepine, 5-(4-Methyl-1-Piperazinyl)-, (Z)-2-Butenedioate(1:1) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.