Description

(+/-)14,15-Epoxyeicosa-5Z,8Z,11Z-Trienoic Acid is a specialized epoxyeicosatrienoic acid (EET) derivative, a key intermediate in the study of cytochrome P450 (CYP) derived eicosanoid signaling pathways. This compound is critical for researchers investigating the biological roles of lipid mediators in cardiovascular, renal, and inflammatory processes. It serves as an essential reference standard and synthetic building block for pharmaceutical R&D, biochemical research, and analytical method development in the life sciences sector.

Application

• Biochemical Research Standard: Used as a high-purity reference material for studying the metabolism and biological activity of epoxyeicosatrienoic acids (EETs).
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel therapeutics targeting cardiovascular diseases, hypertension, and inflammation.
• Metabolic Pathway Analysis: Employed in in vitro and in vivo studies to elucidate the role of soluble epoxide hydrolase (sEH) and CYP epoxygenase pathways.
• Analytical Method Development: Essential for calibrating equipment and validating methods in LC-MS, GC-MS, and HPLC analyses for eicosanoid profiling.
• Cell Signaling Studies: Applied in research to understand the mechanisms of vasodilation, angiogenesis, and cellular protection mediated by epoxy fatty acids.

Basic Information

Product Name	(+/-)14,15-Epoxyeicosa-5Z,8Z,11Z-Trienoic Acid
CAS No.	81276-03-1
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	14,15-EET; 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid; (±)14,15-Epoxyeicosa-5,8,11-trienoic Acid; 14,15-Epoxyeicosatrienoic Acid; 14,15-EEZE; Arachidonic acid 14,15-epoxide; 5Z,8Z,11Z-14,15-Epoxyeicosatrienoic Acid; 20:3n-6 14,15-epoxide
EINECS	Contact for details

Quality Control

Our (+/-)14,15-Epoxyeicosa-5Z,8Z,11Z-Trienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for advanced research applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. For long-term storage, solutions should be prepared in anhydrous, oxygen-free solvents and kept at -80°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 97%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.