Description

(5R)-3-[[(E)-2-(Acetylamino)Ethenyl]Thio]-6-[(E)-2-Hydroxy-1-Methylethylidene]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic β-lactam structure. This compound is of significant value in the research and synthesis of novel antibiotics and other bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of next-generation antimicrobial agents.

Application

• Key Intermediate in β-Lactam Antibiotic Synthesis: Serves as a crucial building block for the research and development of novel penem and carbapenem-class antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry programs to explore new chemical entities with potential antibacterial, antifungal, or enzyme-inhibitory activity.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value active pharmaceutical ingredients (APIs) for preclinical and clinical studies.
• Biochemical Research: Utilized as a substrate or inhibitor in studies targeting bacterial cell wall synthesis enzymes, such as penicillin-binding proteins (PBPs).
• Academic Research: Applied in university and institutional labs for studying the structure-activity relationships (SAR) of β-lactam compounds.

Basic Information

Item	Details
Product Name	(5R)-3-[[(E)-2-(Acetylamino)Ethenyl]Thio]-6-[(E)-2-Hydroxy-1-Methylethylidene]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid
CAS No.	81018-71-5
Molecular Formula	C14H16N2O5S
Molecular Weight	324.35 g/mol
Synonyms	(5R)-3-[(E)-2-(Acetylamino)vinylthio]-6-[(E)-2-hydroxy-1-methylethylidene]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; (5R,6Z)-6-[(1R)-1-Hydroxyethylidene]-3-[(E)-2-(acetylamino)ethenyl]thio-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid; A β-lactam antibiotic intermediate; Penem derivative intermediate
EINECS	Contact for details

Quality Control

Our (5R)-3-[[(E)-2-(Acetylamino)Ethenyl]Thio]-6-[(E)-2-Hydroxy-1-Methylethylidene]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.