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Acarviosin CAS NO 80943-41-5


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CAS No.:80943-41-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Acarviosin is a potent α-glucosidase inhibitor, a key structural component of the complex oligosaccharide antibiotic acarbose. This compound is of significant interest in pharmaceutical research and development due to its specific enzyme inhibition properties, which are crucial for metabolic studies. It serves as a critical intermediate and reference standard for the synthesis and quality control of anti-diabetic drugs. Researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors require high-purity Acarviosin for developing new therapeutic agents and analytical methods.

Application

  • Pharmaceutical Intermediate: Serves as a core building block for the synthesis of acarbose and related α-glucosidase inhibitor drugs.
  • Biochemical Research: Used as a reference standard and tool compound in enzymatic studies targeting carbohydrate metabolism pathways.
  • Drug Discovery: Employed in high-throughput screening and development of novel therapeutic agents for diabetes mellitus and related metabolic disorders.
  • Quality Control & Analytical Standards: Essential for HPLC and LC-MS method development, validation, and as a certified reference material in pharmaceutical quality assurance labs.
  • Academic Research: Utilized in universities and research institutes for investigating enzyme kinetics, inhibition mechanisms, and glycobiology.

Basic Information

Product Name Acarviosin
CAS No. 80943-41-5
Molecular Formula C8H15NO5
Molecular Weight 205.21 g/mol
Synonyms Acarviosine; (2R,3R,4R,5S)-2-(Hydroxymethyl)-5-(4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl)amino)tetrahydro-2H-pyran-3,4-diol; O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-1-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-D-glucose fragment; Acarbose hydrolysate fragment; α-glucosidase inhibitor core.
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Quality Control

Our Acarviosin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results. We support compliance with cGMP and ISO standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm
Related Substances (HPLC) Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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