Description

Amberlite(R) IRP-64 Ion-Exchange Resin is a weakly acidic cation exchange resin based on a methacrylic acid-divinylbenzene copolymer matrix. This product is specifically engineered for pharmaceutical applications, offering high purity and consistent performance as an excipient. It is a critical material for formulators requiring a reliable ion-exchange agent for taste masking, controlled release, and stabilization of active pharmaceutical ingredients (APIs). Industries that rely on this resin include pharmaceutical manufacturing, nutraceuticals, and advanced chemical synthesis.

Application

• Pharmaceutical Taste Masking: Effectively binds bitter-tasting APIs to improve patient compliance in oral dosage forms like tablets and suspensions.
• Controlled Drug Release: Used in sustained-release and modified-release formulations to manage the rate of API delivery in the gastrointestinal tract.
• API Stabilization: Protects acid-sensitive active ingredients from degradation by controlling the local ionic environment.
• Nutraceutical Formulations: Employed in vitamin and mineral supplements for similar taste-masking and stabilization purposes.
• Purification Intermediate: Serves as a processing aid in the purification and isolation of certain pharmaceutical compounds.

Basic Information

Product Name	Amberlite(R) IRP-64 Ion-Exchange Resin
CAS No.	80892-32-6
Molecular Formula	(C5H8O2·C10H10)n
Molecular Weight	Polymeric Material
Synonyms	Polacrilin Potassium; Methacrylic Acid Divinylbenzene Copolymer; Weakly Acidic Cation Exchange Resin; Amberlite IRP 64; Amberlite IRP-64; Polacrilex Resin; Cation Exchange Resin, Weak Acid; Poly(methacrylic acid-co-divinylbenzene); 80892-32-6
EINECS	Contact for details

Quality Control

Our Amberlite IRP-64 is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch is controlled against specifications for identity, assay, particle size distribution, and swelling capacity to ensure batch-to-batch consistency and performance. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results. Our quality system supports compliance with cGMP and relevant pharmacopeial guidelines (USP/NF, Ph. Eur.).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white free-flowing powder
Identification (IR)	Conforms to reference spectrum
Assay (Ion Exchange Capacity)	≥ 10.0 meq/g (dry basis)
Particle Size Distribution	Specified per grade (e.g., >95% passes 100 mesh)
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Microbial Limits	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.