Description

Poly(L-Lactide-Co-Caprolactone-Co-Glycolide) is a synthetic, biodegradable copolymer designed for advanced material applications. This versatile polymer offers a unique balance of degradation rate, mechanical strength, and biocompatibility, making it a critical component for high-performance, resorbable products. It is essential for manufacturers in the biomedical, pharmaceutical, and specialty chemical sectors seeking reliable, high-purity materials for next-generation applications.

Application

• Biomedical Implants: Used in the fabrication of resorbable sutures, surgical meshes, bone fixation devices (pins, screws), and tissue engineering scaffolds.
• Controlled Drug Delivery: Serves as a key excipient in the development of long-acting injectable microspheres, implants, and nanoparticle systems for sustained API release.
• Medical Device Coatings: Applied as a biocompatible and bioresorbable coating for stents, catheters, and other implantable devices to modulate tissue response.
• Advanced 3D Printing: A feedstock material for additive manufacturing (e.g., FDM, SLA) of custom, patient-specific medical models and prototypes.
• Cosmetic & Dermatology: Employed in dermal fillers and other aesthetic medicine products that require controlled degradation within the body.

Basic Information

Product Name	Poly(L-Lactide-Co-Caprolactone-Co-Glycolide)
CAS No.	134490-19-0
Molecular Formula	(C3H4O2)x·(C6H10O2)y·(C4H6O4)z
Molecular Weight	Variable (Depends on monomer ratios and polymerization degree)
Synonyms	PLA-PCL-PGA; Poly(L-lactide-co-ε-caprolactone-co-glycolide); Poly(Lactic-co-Caprolactone-co-Glycolic Acid); PLCG; Resomer® LCG (specific grades); Biodegradable Polyester Terpolymer; Poly(LLA-co-CL-co-GA); Absorbable Polymer
EINECS	Contact for details

Quality Control

Our Poly(L-Lactide-Co-Caprolactone-Co-Glycolide) is manufactured under strict quality systems to ensure batch-to-batch consistency for critical applications. Each lot is characterized for key parameters including inherent viscosity, monomer composition (L-Lactide/Caprolactone/Glycolide ratio), residual monomer content, and glass transition temperature (Tg). Certificates of Analysis (COA) detailing these specifications are provided with every shipment. Production can be aligned with cGMP guidelines for pharmaceutical and medical device applications upon request.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive). For long-term stability, store unopened containers in a freezer at -20°C to -10°C under desiccant. Allow sealed containers to equilibrate to room temperature before opening to prevent moisture condensation. Once opened, use immediately or re-seal under an inert atmosphere (e.g., nitrogen or argon) in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder or granules
Inherent Viscosity (dl/g)	0.2 - 2.0 (Grade dependent)
Monomer Ratio (L-LA:CL:GA)	Customizable (e.g., 70:20:10, 50:40:10, etc.)
Glass Transition Temp (Tg)	15°C - 45°C
Residual Monomers	< 0.5% (by HPLC)
Residual Solvents	Meets ICH Q3C guidelines
Moisture Content (KF)	< 1.0%
Molecular Weight Distribution (Mw/Mn)	< 2.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.