Description

Propanoic Acid, 2-Hydroxy-, Polymer With 2-Hydroxyacetic Acid is a synthetic polymer derived from lactic and glycolic acid units, offering a versatile and biodegradable platform for controlled-release applications. This copolymer is valued for its biocompatibility and predictable degradation profile, making it a critical material for advanced formulation development. It is primarily sought by manufacturers in the pharmaceutical, medical device, and specialty chemical industries seeking reliable, high-purity excipients and polymer matrices.

Application

• Pharmaceutical Excipient: Used as a biodegradable polymer matrix in the formulation of sustained-release and targeted drug delivery systems, including microspheres, implants, and injectable depots.
• Medical Device Fabrication: Serves as a key component in the production of bioresorbable surgical sutures, orthopedic fixation devices, and tissue engineering scaffolds.
• Specialty Coatings & Adhesives: Employed in the development of environmentally friendly, degradable coatings for agricultural chemicals or specialty adhesives.
• Cosmetic & Personal Care: Functions as a film-forming agent or delivery vehicle for active ingredients in advanced skincare and cosmetic formulations.
• Research & Development: Utilized in academic and industrial R&D for studying polymer degradation kinetics, drug-polymer interactions, and new biomaterial applications.

Basic Information

Product Name	Propanoic Acid, 2-Hydroxy-, Polymer With 2-Hydroxyacetic Acid
CAS No.	34346-01-5
Molecular Formula	(C3H4O3)m(C2H2O2)n
Molecular Weight	Varies (Polymer)
Synonyms	Poly(DL-lactic-co-glycolic acid); PLGA; Poly(lactide-co-glycolide); DL-PLGA; Poly(lactic-co-glycolic acid); Lactic/Glycolic Acid Copolymer; (3,6-Dimethyl-1,4-dioxane-2,5-dione) copolymer with 1,4-Dioxane-2,5-dione; Polylactide-co-glycolide
EINECS	Contact for details

Quality Control

Our PLGA is manufactured under strict quality management systems to ensure batch-to-batch consistency critical for pharmaceutical and medical applications. Each lot is characterized for key parameters including inherent viscosity, monomer ratio (Lactide:Glycolide), molecular weight distribution, and residual monomer content. A comprehensive Certificate of Analysis (COA) documenting these specifications is provided with every shipment to support your regulatory and formulation needs.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive). Store in a cool, dry place at a controlled room temperature (15-25°C) under dry conditions to prevent hydrolysis and maintain polymer integrity. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white powder or granules
Identification (IR)	Conforms
Lactide:Glycolide Ratio	50:50, 75:25, 85:15 (or as specified)
Inherent Viscosity (dl/g)	0.15 - 0.80 (or as specified)
Molecular Weight (Mw)	5,000 - 100,000 Da (or as specified)
Residual Monomers	< 0.5% (by HPLC)
Residual Solvents	Meets ICH guidelines
Glass Transition Temp (Tg)	40 - 55 °C (DSC)
Moisture Content	< 1.0% (KF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.