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Poly(L-Lactide Glycolide) CAS NO 30846-39-0
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CAS No.:30846-39-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Poly(L-Lactide Glycolide) is a biodegradable, biocompatible copolymer synthesized from L-lactide and glycolide monomers. This material is engineered to provide controlled degradation rates and mechanical properties, making it a cornerstone for advanced, resorbable medical and pharmaceutical applications. It is essential for manufacturers in the biomedical, pharmaceutical, and controlled-release agrochemical sectors seeking reliable, high-purity polymer matrices.
Application
- Resorbable Medical Devices: Key component in the manufacture of surgical sutures, staples, bone screws, plates, and other orthopedic fixation devices.
- Drug Delivery Systems: Matrix material for microspheres, nanoparticles, and implants designed for sustained or targeted release of active pharmaceutical ingredients (APIs).
- Tissue Engineering Scaffolds: Used to create three-dimensional, porous scaffolds that support cell growth and tissue regeneration.
- Veterinary Medicine: Employed in long-acting injectable formulations and implantable devices for animal health.
- Controlled-Release Agrochemicals: Carrier for the encapsulation and gradual release of pesticides, herbicides, or fertilizers.
- Advanced Wound Care: Basis for bioresorbable dressings, hemostats, and adhesion barriers.
Basic Information
| Product Name | Poly(L-Lactide Glycolide) |
| CAS No. | 30846-39-0 |
| Molecular Formula | (C3H4O2)m(C2H2O2)n |
| Molecular Weight | Varies by lactide:glycolide (L:G) ratio and polymerization degree |
| Synonyms | Poly(L-Lactic-co-Glycolic Acid); PLGA; Poly(DL-lactic-co-glycolic acid); Poly(lactide-co-glycolide); Poly(lactic-co-glycolic acid); Resomer; (S)-Poly(lactic acid-co-glycolic acid); Poly[(S)-lactide-co-glycolide] |
| EINECS | Contact for details |
Quality Control
Our Poly(L-Lactide Glycolide) is produced under strict quality management systems. Each batch is characterized for critical parameters including monomer ratio (L:G), inherent viscosity, molecular weight distribution, residual monomer content, and glass transition temperature (Tg). Certificates of Analysis (COA) detailing these specifications are provided with every shipment. We support compliance with cGMP, ISO 13485, and relevant pharmacopeial guidelines for medical-grade applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions (e.g., nitrogen atmosphere) after opening to prevent hydrolysis and molecular weight degradation. For long-term storage, consider refrigeration at 2-8°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or granules |
| Identification (IR) | Conforms to structure |
| Lactide:Glycolide (L:G) Ratio | 50:50, 75:25, 85:15, or custom |
| Inherent Viscosity (dl/g) | 0.15 - 1.50 (or as specified) |
| Molecular Weight (Mw) | 10,000 - 200,000 Da |
| Residual Monomers | < 0.5% (by HPLC) |
| Glass Transition Temp (Tg) | 40°C - 55°C (DSC) |
| Moisture Content | < 1.0% (KF) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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