Description

1-(2,3-Xylyl)Piperazine Monohydrochloride is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and custom synthesis facilities engaged in creating new therapeutic agents, particularly within the central nervous system (CNS) and receptor modulator spaces.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological pathways.
• Chemical Synthesis Building Block: Used in the construction of complex molecular architectures for medicinal chemistry and material science applications.
• Ligand and Receptor Research: Employed in biochemical assays and studies involving serotonin, dopamine, or adrenergic receptor systems due to its piperazine core.
• Agrochemical Development: Serves as an intermediate in the synthesis of advanced crop protection agents and pesticides.
• Academic & Industrial Research: Utilized in universities and corporate R&D centers for exploratory chemistry and process development.
• Custom Manufacturing: Supplied to contract development and manufacturing organizations (CDMOs) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	1-(2,3-Xylyl)Piperazine Monohydrochloride
CAS No.	80836-96-0
Molecular Formula	C13H20N2•HCl
Molecular Weight	240.77 g/mol
Synonyms	1-(2,3-Dimethylphenyl)piperazine hydrochloride; 2,3-Xylylpiperazine hydrochloride; 1-(2,3-DMPP) HCl; 1-(2,3-Dimethylphenyl)piperazine monohydrochloride; 1-(2,3-Xylyl)piperazine HCl; 80836-96-0; Piperazine, 1-(2,3-dimethylphenyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,3-Xylyl)Piperazine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.