Description

2(1H)-Quinolinone, 3,4-Dihydro-6-(3-(4-(2-Methoxyphenyl)-1-Piperazinyl )Propyl)- is a high-purity, synthetic organic compound belonging to the quinolinone class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its complex molecular structure, which provides a versatile scaffold for the development of novel therapeutic agents targeting the central nervous system. This compound is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis and optimization of new chemical entities, particularly for neurological and psychiatric applications.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of potential antipsychotic and neuroleptic drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new molecules targeting dopamine and serotonin receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in in-vitro studies to investigate ligand-receptor interactions and pharmacological pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial synthesis of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2(1H)-Quinolinone, 3,4-Dihydro-6-(3-(4-(2-Methoxyphenyl)-1-Piperazinyl )Propyl)-
CAS No.	80834-64-6
Molecular Formula	C23H29N3O2
Molecular Weight	379.50 g/mol
Synonyms	6-[3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl]-3,4-dihydro-1H-quinolin-2-one; OPC-4392; 6-(3-(4-(o-Methoxyphenyl)-1-piperazinyl)propyl)-3,4-dihydro-2(1H)-quinolinone; Tandospirone Intermediate; SM-3997 Intermediate; 80834-64-6; 2-Quinolinone, 3,4-dihydro-6-[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]-
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Quinolinone, 3,4-Dihydro-6-(3-(4-(2-Methoxyphenyl)-1-Piperazinyl )Propyl)- adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical research. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We are committed to meeting the exacting standards required for advanced intermediates in drug development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.