Description

7Beta-(3-Ethyl-cis-Crotonoyloxy)-1Alpha-(2-Methylbutyryloxy)-3,14-Dehydro-Z-Notonipetranone CAS NO 80514-14-3 is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for its role as a key building block in complex organic syntheses.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for advanced pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in laboratory settings.
• Biochemical Research: Investigated for its interaction with specific biological targets and pathways due to its sesquiterpene lactone core.
• Fine Chemical Synthesis: Utilized in the production of other specialized, high-value organic compounds for research purposes.

Basic Information

Product Name	7Beta-(3-Ethyl-cis-Crotonoyloxy)-1Alpha-(2-Methylbutyryloxy)-3,14-Dehydro-Z-Notonipetranone
CAS No.	80514-14-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(3aR,4S,6aR,7R,9aS,9bR)-7-[(2E)-2-Ethylbut-2-enoyl]oxy-4-(2-methylbutanoyl)oxy-3a,4,5,6,6a,7,8,9,9a,9b-decahydro-3H-cyclopenta[f][1]benzoxepine-1,11-dione; 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone; Z-Notonipetranone derivative; Sesquiterpene lactone ester.
EINECS	Contact for details

Quality Control

Our 7Beta-(3-Ethyl-cis-Crotonoyloxy)-1Alpha-(2-Methylbutyryloxy)-3,14-Dehydro-Z-Notonipetranone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.