Description

Urinastatin is a potent glycoprotein and protease inhibitor derived from human urine, widely recognized for its significant anti-inflammatory and cytoprotective properties. This compound is critical in therapeutic applications for managing severe inflammatory conditions and organ dysfunction. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of treatments for acute pancreatitis, septic shock, and other systemic inflammatory response syndromes.

Application

• Pharmaceutical Active Ingredient: Key component in injectable formulations for treating acute pancreatitis and circulatory shock.
• Critical Care Medicine: Used in therapies for sepsis, systemic inflammatory response syndrome (SIRS), and multiple organ dysfunction syndrome (MODS).
• Surgical Adjunct: Administered to mitigate inflammatory responses and improve outcomes following major surgeries, such as cardiovascular and abdominal procedures.
• Research & Development: Essential reference standard and biochemical tool for studying protease inhibition, inflammatory pathways, and ischemia-reperfusion injury in preclinical models.
• Biochemical Reagent: Used in enzymatic assays and diagnostic kit development to study trypsin, chymotrypsin, and elastase activity.

Basic Information

Product Name	Urinastatin
CAS No.	80449-32-7
Molecular Formula	C20H32N4O5S2
Molecular Weight	496.62 g/mol
Synonyms	Ulinastatin; Miraclid; Urinary Trypsin Inhibitor (UTI); Human Urinary Trypsin Inhibitor; Bikunin; HI-30; Inter-α-trypsin inhibitor light chain; MUTI; Urinastatin (bovine); E-3123
EINECS	Contact for details

Quality Control

Our Urinastatin is manufactured under strict quality management systems to ensure the highest standards of purity and biological activity. Each batch is subjected to comprehensive analytical testing, including identity confirmation, potency assay, and impurity profiling. Certificates of Analysis (COA) detailing purity, biological activity (in units), and compliance with relevant specifications are provided to guarantee consistent quality and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Biological Activity	≥ 50,000 U/mg
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Bacterial Endotoxins	< 10 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.