Description

(Z)-2-Methyl-2-Butenoic Acid (3As,4S,6R,8Z,10R,11Ar)-6-Acetoxy-2,3,3A,4,5,6,7,10,11,11A-Decahydro-6,10-Dimethyl-3-Methylene-2,7-Dioxocyclodeca[B]Furan-4-Yl Ester is a high-purity, complex organic ester with a defined stereochemistry, serving as a critical advanced intermediate in specialized chemical synthesis. Its precise molecular architecture makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily targeted at research and development laboratories and production facilities in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in steroid-like or terpenoid-derived drug discovery programs.
• Organic Synthesis Building Block: Used in advanced multi-step organic reactions, including cyclizations and esterifications, to create novel molecular frameworks.
• Medicinal Chemistry Research: Employed in the research and development of new chemical entities (NCEs) for evaluating biological activity and structure-activity relationships (SAR).
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of high-value, low-volume fine chemicals and custom synthesis projects.
• Academic & Institutional Research: Utilized in university and institutional laboratories for methodological studies in synthetic organic chemistry and natural product synthesis.

Basic Information

Item	Details
Product Name	(Z)-2-Methyl-2-Butenoic Acid (3As,4S,6R,8Z,10R,11Ar)-6-Acetoxy-2,3,3A,4,5,6,7,10,11,11A-Decahydro-6,10-Dimethyl-3-Methylene-2,7-Dioxocyclodeca[B]Furan-4-Yl Ester
CAS No.	80398-75-0
Molecular Formula	C22H30O6
Molecular Weight	390.47 g/mol
Synonyms	2-Methyl-2-butenoic acid (3aR,4S,6R,8Z,10R,11aR)-6-(acetyloxy)-2,3,3a,4,5,6,7,10,11,11a-decahydro-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl ester; Tiglic Acid Ester Derivative; (Z)-Tiglate Ester; 6-Acetoxy-6,10-dimethyldecahydro-3-methylenefurano[4,3-b]furan-2,7-dione tiglate; CAS 80398-75-0.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality control protocols to ensure identity, purity, and consistency. We employ analytical techniques including HPLC, GC, and NMR to verify specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.