Description

Piperazine, 1-(1-Oxo-2-Butenyl)- (9Ci) is a specialized piperazine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the production of high-value pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological or infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides where the piperazine moiety imparts specific biological activity.
• Fine Chemical Production: Acts as a building block for creating complex molecules used in dyes, pigments, and advanced material science applications.
• Bioconjugation & Linker Chemistry: The reactive ketone group makes it suitable for use in bioconjugation techniques and as a linker in proteomics and drug delivery system research.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways in heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	Piperazine, 1-(1-Oxo-2-Butenyl)- (9Ci)
CAS No.	80384-98-1
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	1-(1-Oxo-2-butenyl)piperazine; 1-But-2-enoylpiperazine; 1-Crotonoylpiperazine; N-Crotonoylpiperazine; (E)-1-(1-Oxobut-2-en-1-yl)piperazine; Piperazine, 1-(1-oxo-2-butenyl)-; 80384-98-1; 1-(2-Butenoyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(1-Oxo-2-Butenyl)- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications, and our quality commitment ensures you receive a reliable and high-purity intermediate for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.