Description

1-Palmitoyl-2-(9,10-Epoxystearoyl)Phosphatidylcholine is a specialized, semi-synthetic phospholipid derivative featuring an epoxide functional group on one of its fatty acyl chains. This unique structure makes it a valuable biochemical tool and a key intermediate for synthesizing more complex lipid molecules. It is primarily utilized in advanced research and development within the life sciences, particularly for studying membrane biophysics, lipid signaling pathways, and for the development of novel drug delivery systems.

Application

• Biochemical Research: A critical reagent for investigating the role of oxidized phospholipids in cellular processes, inflammation, and signaling.
• Lipidomics & Analytical Standards: Used as a reference standard in mass spectrometry for the identification and quantification of complex lipid species in biological samples.
• Drug Delivery Development: Serves as a functionalized building block for creating targeted liposomal and nanoparticle-based delivery vehicles.
• Membrane Biophysics Studies: Employed in model membrane systems (e.g., liposomes, bilayers) to study the effects of lipid oxidation on membrane structure, fluidity, and protein interactions.
• Enzyme Substrate: Used as a substrate for phospholipase enzymes in mechanistic and kinetic studies.
• Synthetic Intermediate: The reactive epoxide moiety allows for further chemical modification, enabling the synthesis of tailored phospholipids for specific applications.

Basic Information

Product Name	1-Palmitoyl-2-(9,10-Epoxystearoyl)Phosphatidylcholine
CAS No.	80362-01-2
Molecular Formula	C42H80NO9P
Molecular Weight	774.06 g/mol
Synonyms	PEPC; 1-Palmitoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phosphocholine; (9,10-Epoxy)PE; Epoxy phosphatidylcholine; Oxidized Phosphatidylcholine; 1-Palmitoyl-2-(9,10-epoxystearoyl)-sn-glycero-3-phosphocholine; Epoxy-PC; POPC Epoxide Derivative
EINECS	Contact for details

Quality Control

Our high-purity biochemicals are produced and handled under strict quality management protocols. Each batch of 1-Palmitoyl-2-(9,10-Epoxystearoyl)Phosphatidylcholine is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure reproducibility and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation. Once opened, purge the container with dry inert gas (argon or nitrogen) and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98%
Solubility	Soluble in chloroform, ethanol; forms dispersions in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.