Description

5-(4-Chloro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid CAS NO 80356-77-0 is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific chlorophenyl and dicarboxylic acid functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Chelator Development: The dicarboxylic acid groups make it a valuable starting material for creating complexing agents and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Serves as a building block for π-conjugated systems in the development of organic semiconductors and light-emitting materials.
• Chemical Research & Development: Employed as a standard or reference compound in methodological studies and for exploring new organic reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	5-(4-Chloro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid
CAS No.	80356-77-0
Molecular Formula	C13H7ClN2O4
Molecular Weight	290.66 g/mol
Synonyms	5-(4-Chlorophenyl)pyrazine-2,3-dicarboxylic acid; 2,3-Pyrazinedicarboxylic acid, 5-(4-chlorophenyl)-; 4-Chlorophenylpyrazinedicarboxylic Acid; 80356-77-0; 5-(p-Chlorophenyl)pyrazine-2,3-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Chloro-Phenyl)-Pyrazine-2,3-Dicarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.