Description

8(S),15(S)-Dihete is a specialized chiral dihydroxy fatty acid derivative with the CAS registry number 80234-66-8. This compound serves as a critical intermediate and reference standard in advanced biochemical and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents and studying lipid-mediated signaling pathways.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of specialized pro-resolving mediators (SPMs) and other bioactive lipid molecules.
• Biochemical Research: Used as a reference standard in analytical methods (HPLC, LC-MS) for quantifying related eicosanoid pathways.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the role of specific lipoxin and resolvin analogs in inflammation resolution.
• Reference Material: Serves as a high-purity calibrant for quality control in the production of related lipid-based pharmaceuticals.
• Academic Research: A vital tool for universities and research institutes studying the stereochemistry and biological activity of oxylipins.

Basic Information

Product Name	8(S),15(S)-Dihete
CAS No.	80234-66-8
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	8(S),15(S)-DiHETE; (8S,15S)-Dihydroxyicosa-5Z,9E,11Z,13E-tetraenoic Acid; 8,15-DiHETE; 8,15-Dihydroxyeicosatetraenoic Acid; (5Z,9E,11Z,13E)-(8S,15S)-Dihydroxyicosa-5,9,11,13-tetraenoic Acid; 8(S),15(S)-DiHETE free acid; 8,15-DiHETE (8S,15S)
EINECS	Contact for details

Quality Control

Our 8(S),15(S)-Dihete is produced under stringent conditions to ensure high chiral purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Enantiomeric Purity (Chiral HPLC)	≥ 98% ee (8S,15S)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.