Description

Hypromellose is a semi-synthetic, inert, and viscoelastic polymer derived from cellulose, widely recognized for its exceptional utility as a thickening agent, film former, and stabilizer. Its non-ionic nature and compatibility with a broad range of ingredients make it a cornerstone excipient for achieving precise rheological control and drug release profiles. This high-quality cellulose ether is essential for manufacturers in the pharmaceutical, food, and personal care industries seeking reliable performance and regulatory compliance.

Application

• Pharmaceuticals: As a critical binder, coating agent, and controlled-release matrix in tablet and capsule formulations.
• Ophthalmic Solutions: Used as a lubricant and viscosity-enhancing agent in artificial tears and other eye drops.
• Food Industry: Functions as a thickener, emulsifier, and stabilizer in various food products, often meeting FCC standards.
• Cosmetics & Personal Care: Provides suspension, film-forming, and rheology-modifying properties in creams, lotions, and shampoos.
• Construction Materials: Acts as a water-retention agent and workability aid in cement-based products like tile adhesives and renders.
• Industrial Coatings: Serves as a thickener and protective colloid in water-based paints and coatings.

Basic Information

Product Name	Hypromellose
CAS No.	8063-82-9
Molecular Formula	(C6H7O2(OH)3-m-n(OCH3)m(OCH2CH(OH)CH3)n)x
Molecular Weight	~10,000 - 1,500,000 g/mol (Varies by grade and substitution)
Synonyms	Hydroxypropyl Methylcellulose (HPMC); Methyl Hydroxypropyl Cellulose; Cellulose, 2-hydroxypropyl methyl ether; Hypromellosum; Benecel; Methocel; Metolose; Pharmacoat; Culminal
EINECS	232-674-9

Quality Control

Our Hypromellose is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and compliance with major pharmacopoeial standards, including USP-NF, Ph. Eur., and JP. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as viscosity, methoxy and hydroxypropoxy content, pH, and loss on drying. We also offer grades compliant with food (FCC) and industrial specifications to meet diverse application needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption, which can affect flow properties and performance.

Specification

Item	Specification
Appearance	White or off-white fibrous or granular powder
Identification (IR)	Conforms
Viscosity (2% aqueous solution)	As per grade (e.g., 5, 15, 50, 4000, 15000 cP)
Methoxy Content	19.0% - 30.0%
Hydroxypropoxy Content	4.0% - 12.0%
pH (1% solution)	5.0 - 8.0
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.