Description

Insulin, Zinc, Bovine is a crystalline complex of bovine insulin with zinc ions, which stabilizes the hexameric form of the hormone. This formulation is critical for providing a sustained-release profile in therapeutic applications, ensuring prolonged biological activity. It is an essential active pharmaceutical ingredient (API) and research biochemical for manufacturers in the pharmaceutical and biotechnology sectors developing long-acting insulin formulations and conducting metabolic studies.

Application

• Primary Active Pharmaceutical Ingredient (API) in the manufacture of sustained-release, intermediate-acting insulin formulations.
• Critical raw material for biopharmaceutical research and development focusing on diabetes therapeutics.
• Reference standard in quality control laboratories for analytical method development and validation.
• Biochemical reagent for in-vitro metabolic and signaling pathway studies in academic and industrial research.
• Component in cell culture media for specific experimental protocols requiring insulin supplementation.
• Starting material for further chemical modification to create novel insulin analogs.

Basic Information

Product Name	Insulin, Zinc, Bovine
CAS No.	8049-62-5
Molecular Formula	C254H377N65O76S6 • xZn
Molecular Weight	~5733.5 g/mol (for insulin monomer, excluding zinc)
Synonyms	Bovine Insulin Zinc Complex; Zinc Insulin, Bovine; Insulin Zinc Suspension (Bovine); Bovine Insulin Zinc Salt; Insulin (Bovine) Zinc; Depot Insulin (Bovine); Lente Insulin (Bovine); Protamine Zinc Insulin (Bovine); Insulin-Zn; Zn-Insulin
EINECS	232-488-9

Quality Control

Our Insulin, Zinc, Bovine is produced and tested under strict quality management systems. It meets high-purity standards suitable for pharmaceutical research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and related substances. We ensure compliance with relevant guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, keep desiccated under an inert atmosphere at -20°C or below. Allow to equilibrate to room temperature in the unopened container before use to prevent condensation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference spectrum
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Potency	26.0 - 30.0 IU/mg
Zinc Content	0.3% - 0.6%
Related Proteins (HPLC)	Total impurities ≤ 5.0%
Water (Karl Fischer)	≤ 10.0%
Bacterial Endotoxins	< 10.0 IU/mg
Microbial Enumeration	Meets Ph. Eur. / USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.