Description

1-(4-Methylpiperazine)Acetonitrile is a versatile chemical intermediate featuring a reactive nitrile group attached to a substituted piperazine moiety. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the piperazine ring contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other high-value specialty chemicals.
• Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	1-(4-Methylpiperazine)Acetonitrile
CAS No.	874-77-1
Molecular Formula	C7H13N3
Molecular Weight	139.20 g/mol
Synonyms	4-Methyl-1-piperazineacetonitrile; (4-Methylpiperazin-1-yl)acetonitrile; 1-Piperazineacetonitrile, 4-methyl-; N-Methylpiperazineacetonitrile; 4-Methylpiperazine-1-acetonitrile; 1-Cyano-2-(4-methylpiperazino)ethane; Acetonitrile, (4-methyl-1-piperazinyl)-
EINECS	212-857-8

Quality Control

Our 1-(4-Methylpiperazine)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.