Description

4-Chlorophenylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for active ingredient development.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the 4-chlorophenyl moiety into target molecules during the production of active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that incorporate chlorinated aromatic structures.
• Ligand and Catalyst Preparation: Serves as a precursor for the synthesis of specialized ligands and organometallic catalysts used in cross-coupling reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.
• Material Science Research: Facilitates the creation of novel organic compounds and polymers with specific electronic or structural properties.
• Academic and R&D Laboratories: A fundamental tool for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	4-Chlorophenylmagnesium Bromide
CAS No.	873-77-8
Molecular Formula	C6H4ClMgBr
Molecular Weight	215.75 g/mol
Synonyms	(4-Chlorophenyl)magnesium Bromide; p-Chlorophenylmagnesium Bromide; 1-Chloro-4-(bromomagnesio)benzene; Grignard Reagent, p-Chlorophenylmagnesium Bromide; 4-Chloro-1-bromomagnesio-benzene; Magnesium, bromo(4-chlorophenyl)-; Bromo(4-chlorophenyl)magnesium
EINECS	212-842-7

Quality Control

Our 4-Chlorophenylmagnesium Bromide is manufactured under stringent quality protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent reactivity. We provide comprehensive Certificates of Analysis (COA) detailing assay, titration concentration (typically supplied as a solution in THF or diethyl ether), and impurity profiles. Our quality management system is designed to meet the exacting standards of GMP and ISO guidelines for critical raw materials.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere). It is typically supplied and stored as a solution under an inert atmosphere (argon or nitrogen) in a suitable anhydrous solvent. Store in a cool, dry, well-ventilated area, away from strong acids and incompatible materials. Follow all relevant safety data sheet (SDS) instructions for handling.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M to 3.0 M in THF or Et2O (as specified)
Purity (GC/HPLC)	Contact for details
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.