Description

4'-Methoxyacetophenone 2,4-Dinitrophenylhydrazone is a specialized organic derivative of acetophenone, widely recognized as a key analytical reagent and synthetic intermediate. This compound is valued for its role as a derivatization agent for the sensitive detection and quantification of carbonyl compounds, particularly ketones and aldehydes, via spectrophotometric or chromatographic methods. It is primarily utilized by analytical laboratories, research institutions, and chemical manufacturers involved in pharmaceutical development, quality control, and advanced organic synthesis.

Application

• Analytical Derivatization Reagent: Used for the pre-column or post-column derivatization of carbonyl compounds (aldehydes and ketones) in High-Performance Liquid Chromatography (HPLC) and UV-Vis spectroscopy to enhance detection sensitivity.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of ketone-based impurities or degradation products in active pharmaceutical ingredients (APIs) and drug formulations.
• Environmental Analysis: Applied in the analysis of airborne carbonyl pollutants, such as formaldehyde and acetaldehyde, in environmental monitoring and industrial hygiene studies.
• Food and Flavor Chemistry: Utilized for the analysis of flavor compounds, spoilage markers, and process contaminants that contain carbonyl functional groups.
• Organic Synthesis Intermediate: Serves as a precursor or building block in the synthesis of more complex heterocyclic compounds, dyes, and functional materials.
• Academic and Industrial Research: A standard reagent in method development and chemical research for studying carbonyl reactivity and reaction mechanisms.

Basic Information

Product Name	4'-Methoxyacetophenone 2,4-Dinitrophenylhydrazone
CAS No.	854-04-6
Molecular Formula	C15H14N4O5
Molecular Weight	330.30 g/mol
Synonyms	p-Methoxyacetophenone 2,4-Dinitrophenylhydrazone; 1-[4-(Methoxyphenyl)]ethanone 2,4-dinitrophenylhydrazone; 4-Acetylanisole 2,4-DNPH; Acetophenone, 4'-methoxy-, 2,4-dinitrophenylhydrazone; DNPH derivative of 4'-Methoxyacetophenone; 4-Methoxyacetophenone DNP-hydrazone; 4'-Methoxyacetophenone DNPH
EINECS	Contact for details

Quality Control

Our 4'-Methoxyacetophenone 2,4-Dinitrophenylhydrazone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for analytical reagent and research-grade materials. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.