Description

Phenformin Hydrochloride is a synthetic biguanide derivative and pharmaceutical active ingredient. It is a critical intermediate in research and development for metabolic studies. This compound is primarily utilized by pharmaceutical manufacturers and research institutions focused on endocrinology and diabetes research. The material is supplied as a high-purity, fine white to off-white crystalline powder.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of specialized pharmaceutical compounds.
• Biochemical Research: Used in in vitro and in vivo studies investigating insulin sensitivity, glucose metabolism, and mitochondrial function.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Metabolic Pathway Studies: A tool compound for researching the AMP-activated protein kinase (AMPK) pathway and cellular energy regulation.
• Academic Research: Employed in university and institutional research projects exploring historical pharmacological agents and their mechanisms.

Basic Information

Product Name	Phenformin Hydrochloride
CAS No.	834-28-6
Molecular Formula	C10H15N5·HCl
Molecular Weight	241.72 g/mol
Synonyms	Phenformin HCl; 1-Phenethylbiguanide Hydrochloride; N-Phenethylbiguanide Hydrochloride; Phenethylbiguanide Hydrochloride; DBI; INS-1; NSC-73754; Phenformin Monohydrochloride
EINECS	212-629-5

Quality Control

Our Phenformin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) upon request, which include results from HPLC, IR spectroscopy, and residual solvent analysis. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.