Description

1,2-Distearoyl-Sn-Glycero-3-Phosphocholine (DSPC) is a high-purity, synthetic phospholipid that serves as a fundamental building block for advanced lipid-based formulations. Its consistent molecular structure is critical for ensuring the stability, reproducibility, and performance of complex delivery systems. This phospholipid is essential for research and production in the pharmaceutical, biotechnology, and advanced materials sectors, where precise lipid composition directly impacts product efficacy and safety.

Application

• Liposome and Nanoparticle Formulation: A primary component for creating stable, uniform liposomes used in drug delivery, mRNA vaccines, and diagnostic imaging agents.
• Biomimetic Membrane Research: Used to construct model cell membranes (e.g., supported lipid bilayers) for studying membrane proteins, permeability, and cellular interactions.
• Excipient in Injectable Formulations: Acts as a key structural lipid in long-circulating and targeted parenteral drug products.
• Gene Therapy & Nucleic Acid Delivery: A critical ingredient in lipid nanoparticles (LNPs) for encapsulating and protecting siRNA, mRNA, and DNA.
• Cosmetic & Dermal Delivery Systems: Employed in high-end cosmetic products to create nanocarriers for the sustained release of active ingredients.
• Biophysical & Analytical Standards: Serves as a pure reference standard in chromatography (HPLC, TLC) and spectrometry for quality control and research.

Basic Information

Product Name	1,2-Distearoyl-Sn-Glycero-3-Phosphocholine
CAS No.	816-94-4
Molecular Formula	C44H88NO8P
Molecular Weight	790.13 g/mol
Synonyms	DSPC; 1,2-Distearoylphosphatidylcholine; Distearoylphosphatidylcholine; Distearoyl Lecithin; 1,2-Di-O-octadecanoyl-sn-glycero-3-phosphocholine; (2R)-2,3-Bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; Phosphatidylcholine, 1,2-distearoyl-; L-α-Distearoylphosphatidylcholine
EINECS	212-445-9

Quality Control

Our 1,2-Distearoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity, to ensure it meets stringent specifications for critical applications. Certificates of Analysis (COA) with full traceability are provided, and we support compliance with relevant pharmaceutical guidelines (e.g., ICH Q7).

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Approx. 55 - 58 °C
Loss on Drying	≤ 1.0 %
Residual Solvents	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.