Description

1,2-Distearoyl-Rac-Glycero-3-Phosphocholine is a synthetic, high-purity phospholipid widely used as a critical excipient and raw material in advanced pharmaceutical and biotechnological formulations. Its primary value lies in its ability to form stable, well-defined liposomes and lipid nanoparticles, which are essential for modern drug delivery systems. This compound is particularly vital for research and production in the pharmaceutical, cosmetic, and nutraceutical industries, where precise control over particle size and membrane integrity is required.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key structural component for creating stable vesicles used in mRNA vaccines, cancer therapeutics, and other advanced drug delivery platforms.
• Pharmaceutical Excipient: Used as a stabilizing agent and membrane constituent in injectable formulations and parenteral nutrition products.
• Biomembrane Research: Serves as a standard or model phospholipid for studying membrane biophysics, permeability, and protein-lipid interactions in academic and industrial R&D.
• Cosmetic Formulations: Employed in high-end skincare products for its emulsifying properties and ability to enhance the delivery of active ingredients.
• Diagnostic Reagents: Used in the preparation of calibrators, controls, and reagents for clinical diagnostic assays.
• Nutraceutical Encapsulation: Facilitates the encapsulation of sensitive bioactive compounds to improve their stability and bioavailability.

Basic Information

Product Name	1,2-Distearoyl-Rac-Glycero-3-Phosphocholine
CAS No.	816-93-3
Molecular Formula	C44H88NO8P
Molecular Weight	790.13 g/mol
Synonyms	DSPC; 1,2-Distearoyl-sn-glycero-3-phosphocholine; Distearoylphosphatidylcholine; Phosphatidylcholine, 1,2-distearoyl-; 1,2-Di-O-octadecanoyl-rac-glycero-3-phosphocholine; L-α-Phosphatidylcholine, distearoyl; (Rac)-1,2-Distearoyl-3-glycerophosphocholine; 18:0 PC
EINECS	212-425-5

Quality Control

Our 1,2-Distearoyl-Rac-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and related substances, identity confirmation by FT-IR and NMR, and stringent limits for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) to support regulatory filings for pharmaceutical (GMP), cosmetic, and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Phase Transition Temperature (Tm)	Approx. 55°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.