Description

Hyodeoxycholic Acid CAS NO 83-49-8 is a secondary bile acid, a key biochemical intermediate in the metabolism of cholesterol. This compound is of significant value as a high-purity reference standard and a critical starting material for synthesizing other bioactive bile acids and pharmaceutical agents. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical industries, where precise chemical structure and purity are paramount for developing therapeutic compounds and diagnostic tools.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids used in hepatobiliary disease treatment.
• Biochemical Research: Serves as a vital reference standard and reagent in metabolic pathway studies, lipid research, and investigations into cholesterol homeostasis.
• Cell Culture & Biotechnology: Used as a component in specialized media and as a signaling molecule in stem cell differentiation and organoid research.
• Fine Chemical Synthesis: Acts as a chiral building block for the production of complex organic molecules and steroid derivatives.
• Diagnostic Reagents: Employed in the formulation of calibration standards and kits for clinical diagnostics, particularly in liver function tests.
• Cosmetic & Dermatology R&D: Investigated for its potential bioactive properties in advanced skincare formulations.

Basic Information

Product Name	Hyodeoxycholic Acid
CAS No.	83-49-8
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	3α,6α-Dihydroxy-5β-cholan-24-oic Acid; HDCA; Hyodesoxycholic Acid; α-Hyodeoxycholic Acid; 3α,6α-Dihydroxycholanoic Acid; Hyocholic Acid (related); Isoursodeoxycholic Acid (stereoisomer)
EINECS	201-483-5

Quality Control

Our Hyodeoxycholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and melting point, and stringent control of residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Melting Point	196°C - 202°C
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation [α]20/D	+5.0° to +8.0° (c=1, in ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.