Description

D-Erythro-Sphingosine-1-Phosphate (C20 Base) is a high-purity, bioactive sphingolipid metabolite essential for cellular signaling research and development. This compound serves as a critical reference standard and precursor for investigating sphingosine-1-phosphate (S1P) receptor pathways, which are pivotal in immunology, vascular biology, and oncology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutics targeting inflammation, autoimmune diseases, and cancer.

Application

• Biochemical Research: As a key reference standard for studying S1P receptor (S1PR) signaling, cell migration, and proliferation.
• Pharmaceutical Development: A critical intermediate and analytical standard in the synthesis and quality control of S1P pathway-targeting drug candidates.
• Cell Culture & Assays: Used in in vitro studies to modulate cellular processes such as angiogenesis, lymphocyte trafficking, and endothelial barrier function.
• Metabolomics & Lipidomics: An essential analyte for mass spectrometry-based profiling of sphingolipid metabolism in disease models.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) assays to identify and validate novel agonists or antagonists of S1P receptors.
• Academic Research: Fundamental tool for investigating the role of sphingolipids in physiology and pathology across various biological disciplines.

Basic Information

Product Name	D-Erythro-Sphingosine-1-Phosphate (C20 Base)
CAS No.	799812-75-2
Molecular Formula	C20H42NO5P
Molecular Weight	407.52 g/mol
Synonyms	Sphingosine-1-phosphate (C20); D-erythro-S1P; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol 1-Phosphate; S1P; Sphing-4-enine-1-phosphate; D-erythro-Sphingosine 1-Phosphate; (2S,3R,4E)-2-Azaniumyl-4-octadecene-1,3-diol 1-dihydrogen phosphate; SPHINGOSINE-1-PHOSPHATE (C18 BASE)
EINECS	Contact for details

Quality Control

Our D-Erythro-Sphingosine-1-Phosphate (C20 Base) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and bioactive lipids to support your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.