Description

Pyrazine, (5-Isocyanato-4-Methyl-2-Thiazolyl)- (9Ci) is a specialized heterocyclic building block featuring both isocyanate and thiazole functionalities. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its unique reactive sites enable the construction of targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, where the thiazole and isocyanate groups contribute to biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers, coatings, and resins with tailored thermal or chemical resistance properties.
• Chemical Synthesis: Employed in organic synthesis as a versatile reagent for introducing the (5-isocyanato-4-methyl-2-thiazolyl)pyrazine moiety into more complex structures.
• Bioconjugation & Probe Development: The reactive isocyanate group allows for conjugation with amines, making it useful in creating biochemical probes or labeled compounds for diagnostic applications.

Basic Information

Product Name	Pyrazine, (5-Isocyanato-4-Methyl-2-Thiazolyl)- (9Ci)
CAS No.	799283-95-7
Molecular Formula	C9H6N4OS
Molecular Weight	218.23 g/mol
Synonyms	4-Methyl-5-isocyanato-2-thiazolylpyrazine; (5-Isocyanato-4-methyl-2-thiazolyl)pyrazine; 2-(5-Isocyanato-4-methyl-1,3-thiazol-2-yl)pyrazine; 4-Methyl-2-(pyrazin-2-yl)-1,3-thiazol-5-yl isocyanate; Pyrazine, (5-isocyanato-4-methyl-2-thiazolyl)-; 799283-95-7
EINECS	Contact for details

Quality Control

Our Pyrazine, (5-Isocyanato-4-Methyl-2-Thiazolyl)- (9Ci) is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.