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1-(9Z-Octadecenyl)-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) CAS NO 799279-68-8
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CAS No.:799279-68-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(9Z-Octadecenyl)-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) is a high-purity, synthetic phospholipid derivative, specifically an ammonium salt of a lysophosphatidic acid analogue. This compound is a critical intermediate and research-grade biochemical for studying lipid signaling pathways, particularly those involving lysophosphatidic acid (LPA) receptors. It is essential for pharmaceutical R&D, academic research, and the development of lipid-based drug delivery systems where precise molecular structure and purity are paramount.
Application
- Biochemical Research: A key tool for investigating lysophosphatidic acid (LPA) receptor biology, signal transduction, and cellular responses in areas like cell proliferation, migration, and survival.
- Pharmaceutical Development: Serves as a reference standard, intermediate, or active component in the development of novel therapeutics targeting lipid-mediated pathways, including potential anti-cancer and anti-fibrotic agents.
- Lipidomics & Analytical Standards: Used as a high-purity standard for mass spectrometry and chromatography to identify, quantify, and characterize complex lipid mixtures in biological samples.
- Liposome & Nanoparticle Formulation: Employed as a functional excipient to modify the surface properties and targeting capabilities of lipid-based drug delivery vehicles.
- Cell Culture & Media Supplement: Utilized in specialized cell culture applications to study the effects of specific lipid signaling molecules on stem cell differentiation or tissue engineering.
- Enzyme Substrate/Inhibitor Studies: Acts as a substrate for enzymes like phospholipases or autotaxin, facilitating kinetic studies and inhibitor screening in drug discovery.
Basic Information
| Product Name | 1-(9Z-Octadecenyl)-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) |
| CAS No. | 799279-68-8 |
| Molecular Formula | C₂₁H₄₆NO₆P |
| Molecular Weight | 439.57 g/mol |
| Synonyms | 1-O-(9Z-Octadecenyl)-2-hydroxy-sn-glycero-3-phosphate ammonium salt; (9Z)-1-(Octadec-9-enyl)-2-hydroxy-sn-glycero-3-phosphate ammonium salt; 1-Oleyl-2-hydroxy-sn-glycero-3-phosphate ammonium salt; LPA analogue (ammonium salt); 1-O-Octadecenyl-2-hydroxy-sn-glycerol-3-phosphate ammonium salt; 1-(Oleyl)-2-hydroxy-sn-glycero-3-phosphoric acid ammonium salt; sn-1-Oleyl-2-hydroxy-glycerophosphoric acid ammonium salt |
| EINECS | Contact for details |
Quality Control
Our 1-(9Z-Octadecenyl)-2-Hydroxy-Sn-Glycero-3-Phosphate (Ammonium Salt) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for production and can support regulatory filings with appropriate documentation.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or waxy solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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