Description

1-Oleoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is a specialized, high-purity phospholipid derivative, a critical intermediate in advanced biochemical synthesis and pharmaceutical research. Its unique cyclic phosphate structure offers distinct chemical reactivity and stability, making it invaluable for modifying lipid properties and creating novel drug delivery systems. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors, particularly those developing liposomal formulations, prodrugs, and specialized lipid-based nanoparticles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel phospholipid-based prodrugs and active pharmaceutical ingredients (APIs).
• Lipid Nanoparticle (LNP) Research: Used in the development and optimization of next-generation lipid nanoparticles for mRNA and gene therapy delivery systems.
• Liposome Formulation: A functional component for creating specialized liposomes with tailored surface charge and membrane fusion properties for targeted drug delivery.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to phospholipid metabolism and cell signaling pathways.
• Surface Chemistry & Materials Science: Employed to create functionalized lipid monolayers or bilayers on surfaces for biosensor and diagnostic device development.
• Excipient Development: Investigated for use as an innovative solubilizing or stabilizing agent in complex parenteral formulations.

Basic Information

Product Name	1-Oleoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt)
CAS No.	799268-72-7
Molecular Formula	C21H42NO7P
Molecular Weight	451.53 g/mol
Synonyms	1-Oleoyl-2,3-cyclic phosphatidic acid ammonium salt; (9Z)-Octadec-9-enoic acid, 1-[(2,3-cyclic phosphono)oxy]-3-(octadec-9-enoyloxy)propan-2-yl ester, ammonium salt; 1-Oleoyl-2,3-cyclic-PA ammonium salt; 1-Oleoyl-cyclic phosphatidic acid ammonium salt; Oleoyl cyclic phosphatidic acid ammonium salt; cPA(18:1) ammonium salt; Cyclic phosphatidic acid (18:1) ammonium salt; Ammonium 1-oleoyl-sn-glycerol-2,3-cyclic phosphate
EINECS	Contact for details

Quality Control

Our 1-Oleoyl-Sn-Glycero-2,3-Cyclic-Phosphate (Ammonium Salt) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant guidelines for the production of fine chemicals intended for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.